教育背景与工作经历

教育背景

2019.09——2022.06中国科学院化学研究所博士分析化学

2016.09——2019.06中国科学院化学研究所硕士分析化学

2012.09——2016.06北京理工大学本科应用化学

工作经历

2022.07——至今js6668金沙登录入口教学科研

科研成果

文章发表

(1)Li, Y.; Jia, K.; Pan, Y.; Han, J.; Chen, J.; Wang, Y.; Ma, X.; Chen, H.; Wang, S.; Xie, D.; et al. Pocket-Size Wireless Nanoelectrospray Ionization Mass Spectrometry for Metabolic Analysis of Salty Biofluids and Single Cells.Anal. Chem.2023,95(10), 4612-4618. DOI: 10.1021/acs.analchem.2c04268.

(2)Li, Y.; Jiang, L.; Wang, Z.; Wang, Y.; Cao, X.; Meng, L.; Fan, J.; Xiong, C.; Nie, Z. Profiling of Urine Carbonyl Metabolic Fingerprints in Bladder Cancer Based on Ambient Ionization Mass Spectrometry.Anal. Chem.2022,94(27), 9894-9902. DOI: 10.1021/acs.analchem.2c01890.

(3)Li, Y.; Chen, J.; Meng, L.; He, L.; Liu, H.; Xiong, C.; Nie, Z. Pocket-Size "MasSpec Pointer" for Ambient Ionization Mass Spectrometry.Anal. Chem.2021,93(39), 13326-13333. DOI: 10.1021/acs.analchem.1c03087.

(4)Li, Y.; Meng, L.; Wang, G.; Zhou, X.; Ouyang, Z.; Nie, Z. A Gas-Phase Reaction Accelerator Using Vortex Flows.Anal. Chem.2020,92(17), 12049-12054. DOI: 10.1021/acs.analchem.0c02672.

(5) Fan, J.; Wang, X.; Yu, Y.;Li, Y.*; Nie, Z.* Screening of hepatocellular carcinoma via machine learning based on atmospheric pressure glow discharge mass spectrometry.Analyst2023,148(2), 337-343. DOI: 10.1039/d2an01756c.

(6)Li, Y.; Meng, L.; Li, Z.; Wang, Y.; Wang, X.; Liu, H.; Xiong, C.; Nie, Z. Hand-powered ionization methods for the mass spectrometric detection of small molecules.Int. J. Mass spectrom.2021,470, 116716. DOI: 10.1016/j.ijms.2021.116716.

(7) Chen, J.;Li, Y.; Jiang, Y.; Mao, L.; Lai, M.; Jiang, L.; Liu, H.; Nie, Z. TiO2/MXene‐Assisted LDI‐MS for Urine Metabolic Profiling in Urinary Disease.Adv. Funct. Mater.2021,31(52). DOI: 10.1002/adfm.202106743.

(8) Li, Z.;Li, Y.; Zhan, L.; Meng, L.; Huang, X.; Wang, T.; Li, Y.; Nie, Z. Point-of-Care Test Paper for Exhaled Breath Aldehyde Analysis via Mass Spectrometry.Anal. Chem.2021,93(26), 9158-9165. DOI: 10.1021/acs.analchem.1c01011.

(9) Wang, Y.;Li, Y.; Wang, X.; Yu, D.; Nie, Z. Rapid detection and classification of hongmu by atmospheric pressure ionization mass spectrometry.Analyst2022,147(21), 4857-4865. DOI: 10.1039/d2an01169g.

(10) Wang, X.;Li, Y.; Jiang, Y.; Meng, L.; Nie, Z. In-depth free fatty acids annotation of edible oil by mCPBA epoxidation and tandem mass spectrometry.Food Chem.2022,374, 131793. DOI: 10.1016/j.foodchem.2021.131793.

(11) Liu, C.;Li, Y.; Xiong, C.; Nie, Z. Development of capillary-paper spray for small-molecule analysis in complex samples.Anal Bioanal Chem2021,413(4), 1099-1106. DOI: 10.1007/s00216-020-03072-y.

(12) Xiong, C.; Liu, H.;Li, Y.; Meng, L.; Wang, J.; Nie, Z. High Speed Mass Measurement of a Single Metal-Organic Framework Nanocrystal in a Paul Trap.Anal. Chem.2022,94(6), 2686-2692. DOI: 10.1021/acs.analchem.1c03845.

(13) Cai, M.; Xu, K.;Li, Y.; Nie, Z.; Zhang, L.; Luo, S. Chiral Primary Amine/Ketone Cooperative Catalysis for Asymmetric alpha-Hydroxylation with Hydrogen Peroxide.J. Am. Chem. Soc.2021,143(2), 1078-1087. DOI: 10.1021/jacs.0c11787.

(14) Jiang, Y.; Sun, J.; Xiong, C.; Liu, H.;Li, Y.; Wang, X.; Nie, Z. Mass Spectrometry Imaging Reveals In Situ Behaviors of Multiple Components in Aerosol Particles.Angew. Chem. Int. Ed. Engl.2021,60(43), 23225-23231. DOI: 10.1002/anie.202103874.

(15) Cao, J.; Liu, C.; Wang, Q.;Li, Y.; Yu, Q. A novel catalytic application of heteropolyacids: chemical transformation of major ginsenosides into rare ginsenosides exemplified by Rg1.Science China Chemistry2017,60(6), 748-753. DOI: 10.1007/s11426-016-0439-6.

(16) He, L.; Wang, X.; Chen, J.;Li, Y.; Wang, L.; Xiong, C.; Nie, Z. Biofluids Metabolic Profiling Based on PS@Fe3O4-NH2 Magnetic Beads-Assisted LDI-MS for Liver Cancer Screening.Anal. Chem.2022,94(29), 10367-10374. DOI: 10.1021/acs.analchem.2c00654.

申请及授权专利

1.聂宗秀;李玉泽 等.用于飞行时间质谱仪的金属镀层氧化铝陶瓷电极片.中国, ZL201811222588X.

2.聂宗秀;李玉泽 等.用于质谱反应加速和信号增强的涡流管及实现方法.中国, ZL2019104197844.

3.聂宗秀;李玉泽 等.一种基于质谱的复杂样品实时在线分析平台.申请号: 2020112606499.

4.聂宗秀;李玉泽 等.用于质谱分析的手持式无线离子源.申请号：2021109356825.

5.聂宗秀;李玉泽 等.手持式离子源装置以及质谱仪.国际申请号：PCT/CN2021/134024

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